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抑制胰岛素介导的β2上腺素受体激活 防止糖尿病相关的心脏功能障碍

Qingtong Wang1,2, Yongming Liu1,3, Qin Fu1,4

  • 1Department of Pharmacology, University of California at Davis, CA 95616, USA.

Circulation
|November 6, 2016
PubMed
概括

在2型糖尿病和肥胖症中,高胰岛素血症通过增加PDE4D表达增加心力衰竭的风险. 向β- 2上腺素受体或GRK2可以预防这种心脏功能障碍.

关键词:
糖尿病心肌病心脏衰竭胰岛素基化酶β-上腺体受体

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