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通过向PI3Kγ在骨髓细胞中克服对检查点阻塞治疗的抵抗

Olivier De Henau1, Matthew Rausch2, David Winkler2

  • 1Memorial Sloan Kettering Cancer Center, Parker Institute for Cancer Immunotherapy and Swim Across America/Ludwig Collaborative Laboratory, New York, New York 10065, USA.

Nature
|November 10, 2016
PubMed
概括

用PI3Kγ抑制剂向髓状细胞可以克服对癌症免疫治疗的抵抗力. 这种方法重塑瘤的免疫微环境,恢复对免疫检查点阻断抗体的敏感性.

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