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感应DNA的AIM2炎症酶控制辐射诱导的细胞死亡和组织损伤

Bo Hu1, Chengcheng Jin1, Hua-Bing Li1

  • 1Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA.

Science (New York, N.Y.)
|November 16, 2016
PubMed
概括

没有AIM2DNA传感器的小鼠受到辐射损伤的保护. 在DNA破裂后, AIM2 触发了肠道和骨髓中的细胞死亡,

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