体自主流出是同情的
I Espinosa-Medina1, O Saha1, F Boismoreau1
1Institut de Biologie de l'École Normale Supérieure (IBENS), INSERM, CNRS, École Normale Supérieure, Paris Sciences et Lettres Research University, Paris, 75005 France.
概括
长期以来被认为是副交感的神经系统,实际上与交感神经系统有共同的特征. 这一发现重新定义了自主神经系统.
科学领域:
- 神经科学
- 发育生物学
- 进化生物学
背景情况:
- 自主神经系统 (ANS) 传统上被分为副交感和胸腔交感外流.
- 控制排便和排尿等功能的骨盆内脏神经被归类为副交感神经,起源于神经神经.
研究的目的:
- 重新评估自主神经系统中神经外流神经元的分类.
- 研究大脑和神经外流的表型和本体特征.
主要方法:
- 对15种表型和本体遗传特征进行比较分析.
- 在副交感和胸腔交感外流中区分前和后神经元.
- 根据这些已确定的标准来评估神经外流.
主要成果:
- 根据所有15个特征,神经外流神经元与胸脊交感神经元是不可区分的.
- 大脑外流神经元表现出不同的特征,使它们与胸神经元区分开来.
- 这挑战了一个世纪的圣神经分类纯粹是副交感的.
结论:
- 自主神经系统可能具有双重结构,其中神经专门服务于副交感功能,脊髓神经 (胸部至神经) 服务于交感功能.
- 这一修订后的框架为骨盆神经生理学,自主发育和进化提供了新的见解.
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