在冠状动脉外科研究 (CASS) 注册表中的无症状左主冠状动脉疾病
H A Taylor1, N J Deumite, B R Chaitman
1Department of Medicine, University of Alabama Medical Center, Birmingham 35294.
Circulation
|June 1, 1989
概括
很少有患有左主冠状动脉疾病的患者无症状. 与医疗管理相比,手术治疗显著改善了无症状个体的生存率.
科学领域:
- 心脏病学 心脏病学
- 心血管外科心血管外科
- 临床研究 临床研究
背景情况:
- 左主冠状动脉疾病 (LMCA) 影响了大量接受冠状动脉扫描的患者.
- 一小部分患有LMCA疾病的患者无症状,这是一种独特的临床挑战.
研究的目的:
- 调查LMCA疾病无症状患者的特征.
- 为了比较医疗与手术管理在无症状LMCA疾病患者的结果.
主要方法:
- 来自冠状动脉外科研究 (CAS) 登记册的数据分析.
- 无症状和症状LMCA疾病患者之间的临床特征和生存率的比较.
主要成果:
- 无症状和症状的LMCA疾病患者表现出类似的狭窄严重程度,冠状动脉疾病的程度和左心室功能.
- 无症状LMCA疾病的手术治疗产生了88%的5年生存率,明显高于医疗管理下57%的生存率 (p=0.02).
结论:
- 无症状的LMCA疾病患者与有症状的同行有相似的疾病严重程度和心脏功能.
- 与非手术方法相比,手术干预在无症状LMCA疾病中提供更好的长期存活率.
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