人体免疫细胞表观遗传和转录变异的遗传驱动因素

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Updated: Mar 11, 2026

A Semiautomated ChIP-Seq Procedure for Large-scale Epigenetic Studies
08:04

A Semiautomated ChIP-Seq Procedure for Large-scale Epigenetic Studies

Published on: August 13, 2020

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Lu Chen1, Bing Ge2, Francesco Paolo Casale3

  • 1Department of Human Genetics, The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1HH, UK; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Long Road, Cambridge CB2 0PT, UK.

Cell
|November 19, 2016
PubMed
概括

这项研究绘制了影响免疫细胞基因表达的遗传和表观遗传因素. 这些发现揭示了这些分子特征如何关联和影响复杂疾病风险,为人类遗传学研究提供了宝贵的资源.

关键词:
DNA 甲基化欧洲安全系统在 QTL基因组特异性基质子的修改免疫性单细胞中性细胞一个T细胞转录方式

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