乳腺癌
Nadia Harbeck1, Michael Gnant2
1Breast Center, Department of Gynecology and Obstetrics, Comprehensive Cancer Center of the Ludwig-Maximilians-University, Munich, Germany.
Lancet (London, England)
|November 21, 2016
概括
乳腺癌治疗正在发展, 专注于个性化治疗以避免过度治疗或治疗不足. 系统和局部治疗的进展,包括针对特定亚型的新辅助方法,改善了早期和转移性乳腺癌患者的结果.
科学领域:
- 癌症学
- 医学研究
背景情况:
- 乳腺癌是全球主要的恶性瘤,
- 治疗策略已经进步,强调个性化治疗以平衡疗效和尽量减少副作用.
研究的目的:
- 审查早期和转移性乳腺癌的当前治疗概念.
- 强调基于分子亚型和疾病负担的量身定制治疗策略的转变.
主要方法:
- 对乳腺癌治疗当前进展的回顾.
- 对早期和转移性疾病的治疗模式的分析.
主要成果:
- 新辅助疗法越来越多地用于HER2阳性和三阴性早期乳腺癌.
- 转移性乳腺癌的治疗方案侧重于延长存活时间和生活质量,并有新兴的向治疗方法.
结论:
- 考虑分子亚型和瘤负载的多学科决策对于最佳的乳腺癌治疗至关重要.
- 内分泌治疗,HER2向和新型向药物的进步为转移性乳腺癌提供了更好的长期疾病控制.
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