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Updated: Aug 7, 2026

In Situ Detection of Autoreactive CD4 T Cells in Brain and Heart Using Major Histocompatibility Complex Class II Dextramers
13:10

In Situ Detection of Autoreactive CD4 T Cells in Brain and Heart Using Major Histocompatibility Complex Class II Dextramers

Published on: August 1, 2014

对表达于外血糖的I类基因相容性抗原的耐受性

G Morahan1, J Allison, J F Miller

  • 1Walter and Eliza Hall Institute of Medical Research, Royal Melbourne Hospital, Victoria, Australia.

Nature
|June 22, 1989
PubMed
概括

对自我抗原的外周耐受性至关重要. 这项研究表明,在转基因小鼠中,依赖于持续的抗原暴露和低联素-2 (IL-2) 水平,诱导了额外的耐受性,从而预防了自身免疫性糖尿病.

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