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生殖细胞瘤中的基因组进化和化学抵抗

Amaro Taylor-Weiner1,2, Travis Zack1,3, Elizabeth O'Donnell4,5

  • 1Division of Medical Sciences, Harvard University, Boston, Massachusetts 02115, USA.

Nature
|December 2, 2016
PubMed
概括

胚胎细胞瘤 (GCTs) 呈现出独特的基因组变异,包括重复的染色体臂放大和删除. 这些基因组特征影响了GCT发育,化疗敏感性和耐药性.

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