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相关概念视频

Nuclear Stability03:18

Nuclear Stability

Protons and neutrons, collectively called nucleons, are packed together tightly in a nucleus. With a radius of about 10−15 meters, a nucleus is quite small compared to the radius of the entire atom, which is about 10−10 meters. Nuclei are extremely dense compared to bulk matter, averaging 1.8 × 1014 grams per cubic centimeter. If the earth’s density were equal to the average nuclear density, the earth’s radius would be only about 200 meters.
To hold positively charged protons together in the...
Nuclear Binding Energy02:13

Nuclear Binding Energy

The difference between the calculated and experimentally measured masses is known as the mass defect of the atom. In the case of helium-4, the mass defect indicates a “loss” in mass of 4.0331 amu – 4.0026 amu = 0.0305 amu. The loss in mass accompanying the formation of an atom from protons, neutrons, and electrons is due to the conversion of that mass into energy that is evolved as the atom forms. The nuclear binding energy is the energy produced when the atoms’ nucleons are bound together;...
Nuclear Fission02:50

Nuclear Fission

Many heavier elements with smaller binding energies per nucleon can decompose into more stable elements that have intermediate mass numbers and larger binding energies per nucleon—that is, mass numbers and binding energies per nucleon that are closer to the “peak” of the binding energy graph near 56. Sometimes neutrons are also produced. This decomposition of a large nucleus into smaller pieces is called fission. The breaking is rather random with the formation of a large number of different...
Nuclear Power02:36

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Controlled nuclear fission reactions are used to generate electricity. Any nuclear reactor that produces power via the fission of uranium or plutonium by bombardment with neutrons has six components: nuclear fuel consisting of fissionable material, a nuclear moderator, a neutron source, control rods, reactor coolant, and a shield and containment system.
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Nuclear fuel consists of a fissile isotope, such as uranium-235, which must be present in sufficient quantity to provide a...
Nuclear Fusion02:45

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The process of converting very light nuclei into heavier nuclei is also accompanied by the conversion of mass into large amounts of energy, a process called fusion. The principal source of energy in the sun is a net fusion reaction in which four hydrogen nuclei fuse and ultimately produce one helium nucleus and two positrons.
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Preparation and Reactivity of Gasless Nanostructured Energetic Materials
09:50

Preparation and Reactivity of Gasless Nanostructured Energetic Materials

Published on: April 2, 2015

形成一个核保护

Jörg Renkawitz1, Michael Sixt1

  • 1Institute of Science and Technology Austria (IST Austria), am Campus 1, 3400 Klosterneuburg, Austria.

Cell
|December 3, 2016
PubMed
概括
此摘要是机器生成的。

在移动细胞中,formin FMN2蛋白在细胞核周围形成一种保护性actin结构. 当细胞挤进狭窄的空间时, 这种半核性行为细胞骨架保护细胞核及其DNA.

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科学领域:

  • 细胞生物学
  • 细胞骨动力学
  • 核力学

背景情况:

  • 细胞迁移对于发育和疾病至关重要.
  • 通过封闭的环境迁移时必须保护核.
  • 在细胞形状和运动中发挥关键作用.

研究的目的:

  • 在细胞迁移过程中调查formin FMN2在核保护中的作用.
  • 阐明周核动因细胞骨保护基因组内容的机制.

主要方法:

  • 移动细胞的活细胞成像.
  • 光显微镜可视化行为和核结构.
  • 为了研究FMN2功能而进行基因操纵.

主要成果:

  • 胺FMN2对于组织周核动素细胞骨至关重要.
  • 这种actin结构直接包围并支持核.
  • 缺乏功能性FMN2的细胞在通过收缩迁移时会增加核变形和DNA损伤.

结论:

  • 形成FMN2组织一个保护性周核动因细胞骨.
  • 这种结构对于在物理压力下迁移细胞的核完整性和基因组稳定性至关重要.