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使用双光子激发光近场扫描光学显微镜研究单个隔离黄金量子点的增强发射

Neranga Abeyasinghe1, Santosh Kumar2, Kai Sun3

  • 1Department of Chemistry, University of Michigan , Ann Arbor, Michigan 48109, United States.

Journal of the American Chemical Society
|December 14, 2016
PubMed
概括

研究人员开发了一种新方法,使用先进的显微镜对个别黄金量子集群 (NC) 进行成像. 这种技术实现了30纳米分辨率,使得超敏感传感和生物成像领域的新应用成为可能.

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Super-resolution fluorescence microscopy (SRFM) provides a better resolution than conventional fluorescence microscopy by reducing the point spread function (PSF). PSF is the light intensity distribution from a point that causes it to appear blurred. Due to PSF, each fluorescing point appears bigger than its actual size, and it is the PSF interference of nearby fluorophores that causes the blurred image. Various approaches to achieving higher resolution through SRFM have recently been...
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