Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Action Potential01:14

Action Potential

11.8K
Neurons communicate by firing action potentials—the electrochemical signal that is propagated along the axon. The signal results in the release of neurotransmitters at axon terminals, thereby transmitting information to the nervous system. An action potential is a specific "all-or-none" change in membrane potential that results in a rapid spike in voltage.
Membrane potential in neurons
Neurons typically have a resting membrane potential of about -70 millivolts (mV). When they receive...
11.8K
Motor and Sensory Areas of the Cortex01:14

Motor and Sensory Areas of the Cortex

8.7K
The cerebral cortex, the brain's outermost layer, is pivotal in processing complex cognitive tasks, emotions, and various sensory inputs and executing voluntary motor activities. This intricate structure is divided into three primary functional areas: the motor areas, sensory areas, and association areas.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex....
8.7K
Somatosensory, Motor, and Association Cortex01:23

Somatosensory, Motor, and Association Cortex

3.4K
The somatosensory cortex in the parietal lobes is crucial for interpreting sensory data such as touch, temperature, and proprioception. The somatosensory cortex, situated in the parietal lobes, plays a vital role in interpreting sensory information like touch, temperature, and proprioception—awareness of body position. This specialized brain region features an organized structure wherein neurons at the top primarily process sensations originating from the lower body. In contrast, those at...
3.4K
Postsynaptic Potential (PSP)01:32

Postsynaptic Potential (PSP)

7.3K
Postsynaptic potential (PSP) refers to a change in the electrical potential of a neuron when neurotransmitters released by presynaptic neurons bind to postsynaptic receptors. This potential can either be excitatory, leading to depolarization and ultimately action potential generation, or inhibitory, leading to hyperpolarization and suppression of the postsynaptic neuron.
There are two types of receptors: ionotropic and metabotropic.
The ionotropic receptor is the membrane protein that has an...
7.3K
The Role of Ion Channels in Neuronal Computation01:19

The Role of Ion Channels in Neuronal Computation

4.1K
A postsynaptic neuron usually receives numerous impulses from several other presynaptic neurons. The axon hillock of the postsynaptic neuron integrates all these signals and determines the likelihood of firing an action potential.
Sometimes a single EPSP is strong enough to induce an action potential in the postsynaptic neuron. However, multiple presynaptic inputs must often create EPSPs around the same time for the postsynaptic neuron to be sufficiently depolarized to fire an action potential....
4.1K
Neuroplasticity01:01

Neuroplasticity

2.2K
Neuroplasticity reflects the brain's remarkable capacity to adapt and evolve, responding dynamically to learning, experiences, or injury by reorganizing its neural circuitry. This reorganization involves creating new neural connections and refining old ones through a series of biological processes that contribute to the brain's lifelong development and adaptability.
2.2K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Tuft dendrites in frontal motor cortex enable flexible learning.

Science (New York, N.Y.)·2026
Same author

Outplaying elite table tennis players with an autonomous robot.

Nature·2026
Same author

The Conformational Switches of a Bacterial Light-Driven Sodium Pump Characterized by Time-Resolved Resonance Raman Spectroscopy.

Chemphyschem : a European journal of chemical physics and physical chemistry·2026
Same author

Whisker-based spatial cognition in mice.

Current biology : CB·2026
Same author

Distinct roles of cortical layer 5 subtypes in associative learning.

Nature communications·2026
Same author

The layer 6b theory of attention.

Neuron·2026

相关实验视频

Updated: Mar 9, 2026

Multiscale Investigations of Cortical Processing by Integrating Laminar Polytrodes and Optogenetics with Micro Electrocorticography in Rodents
07:52

Multiscale Investigations of Cortical Processing by Integrating Laminar Polytrodes and Optogenetics with Micro Electrocorticography in Rodents

Published on: May 23, 2025

921

活跃的皮质树突可以调节感知.

Naoya Takahashi1, Thomas G Oertner2, Peter Hegemann3

  • 1Institute for Biology, Neuronal Plasticity, Humboldt Universität zu Berlin, D-10117, Berlin, Germany.

Science (New York, N.Y.)
|December 24, 2016
PubMed
概括
此摘要是机器生成的。

感知的神经机制仍然不清楚. 鼠标5层金字塔神经元树突中的活性与胡须检测值相关,因果关系树突活动与感知.

更多相关视频

Multi-layer Cortical Ca2+ Imaging in Freely Moving Mice with Prism Probes and Miniaturized Fluorescence Microscopy
10:35

Multi-layer Cortical Ca2+ Imaging in Freely Moving Mice with Prism Probes and Miniaturized Fluorescence Microscopy

Published on: June 13, 2017

32.3K
Multi-electrode Array Recordings of Neuronal Avalanches in Organotypic Cultures
16:01

Multi-electrode Array Recordings of Neuronal Avalanches in Organotypic Cultures

Published on: August 1, 2011

27.0K

相关实验视频

Last Updated: Mar 9, 2026

Multiscale Investigations of Cortical Processing by Integrating Laminar Polytrodes and Optogenetics with Micro Electrocorticography in Rodents
07:52

Multiscale Investigations of Cortical Processing by Integrating Laminar Polytrodes and Optogenetics with Micro Electrocorticography in Rodents

Published on: May 23, 2025

921
Multi-layer Cortical Ca2+ Imaging in Freely Moving Mice with Prism Probes and Miniaturized Fluorescence Microscopy
10:35

Multi-layer Cortical Ca2+ Imaging in Freely Moving Mice with Prism Probes and Miniaturized Fluorescence Microscopy

Published on: June 13, 2017

32.3K
Multi-electrode Array Recordings of Neuronal Avalanches in Organotypic Cultures
16:01

Multi-electrode Array Recordings of Neuronal Avalanches in Organotypic Cultures

Published on: August 1, 2011

27.0K

科学领域:

  • 神经科学是一个神经科学.
  • 感官感知是一种感官感知.
  • 计算神经科学是一种神经科学.

背景情况:

  • 感官知觉的神经支尚未完全理解.
  • 缺乏对知觉如何运作的机械解释.

研究的目的:

  • 为了研究感知检测的神经基础.
  • 探索活跃树突机制在感官感知中的作用.

主要方法:

  • 记录了小鼠初级体感皮质 (S1) 中第5层 (L5) 金字塔神经元的尖端树突中的 (Ca2+) 活性.
  • 与感知值相关的神经元活动用于胡须偏移检测.
  • 操纵角树突活动以评估与感知的因果关系.

主要成果:

  • 发现L5角树突中的Ca2+活动与胡须刺激的感知检测值之间存在相关性.
  • 证明改变顶端树突活动因果关系地影响了感知值.

结论:

  • 在L5金字塔神经元中的活跃树突机制因果关系地参与感知检测.
  • 提供了对体感觉感知神经基础的机械洞察.