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Updated: May 5, 2026

Protocol for the Solid-phase Synthesis of Oligomers of RNA Containing a 2'-O-thiophenylmethyl Modification and Characterization via Circular Dichroism
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Protocol for the Solid-phase Synthesis of Oligomers of RNA Containing a 2'-O-thiophenylmethyl Modification and Characterization via Circular Dichroism

Published on: July 28, 2017

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下游的寡核酸强烈增强了GMP与RNA原型复合物的亲和力

Chun Pong Tam1,2, Albert C Fahrenbach1,3, Anders Björkbom1,4

  • 1Howard Hughes Medical Institute, Department of Molecular Biology and Center for Computational and Integrative Biology, Massachusetts General Hospital , 185 Cambridge Street, Boston, Massachusetts 02114, United States.

Journal of the American Chemical Society
|January 6, 2017
PubMed
概括

另一种GMP并没有显著改善瓜诺辛5'-单酸盐 (GMP) 与RNA模板的结合. 然而,辅助性寡核酸显著增强了GMP结合亲和力,为早期RNA复制提供了洞察力.

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