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Updated: Mar 9, 2026

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艾滋病毒-1链转移复合体的冷EM结构和原子模型

Dario Oliveira Passos1, Min Li2, Renbin Yang2

  • 1Laboratory of Genetics and Helmsley Center for Genomic Medicine, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.

Science (New York, N.Y.)
|January 7, 2017
PubMed
概括

研究人员揭示了HIV-1链转移复合体 (STC) 的高分辨率冷电子显微镜结构. 这种结构阐明了人类免疫缺陷病毒1型 (HIV-1) 常见的Intasome核心架构如何容纳不同的整合酶 (IN) 域模块进行组装.

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