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Updated: Mar 8, 2026

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通过烯修饰替代的聚合物:用于治疗性蛋白质稳定性的快速多样化

Emma M Pelegri-O'Day1, Samantha J Paluck1, Heather D Maynard1

  • 1Department of Chemistry and Biochemistry and California NanoSystems Institute, University of California, Los Angeles , 607 Charles E. Young Drive East, Los Angeles, California 90095, United States.

Journal of the American Chemical Society
|January 13, 2017
PubMed
概括

合成了新型可降解聚合物,以稳定治疗性蛋白质,如颗粒细胞殖民地刺激因子 (G-CSF),以应对储存和运输期间的温度波动. 在蛋白质稳定方面,用三和替代的聚合物是最有前途的.

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The introduction of polyesters has brought major development to the textile industry. The wrinkle-free behavior of polyester blends has eliminated the need for starching and ironing clothes.
Polyesters are commonly prepared from terephthalic acid and ethylene glycol; the crude product is known as poly(ethylene terephthalate) or PET. However, polyesters are synthesized industrially by transesterification of dimethyl terephthalate with ethylene glycol at 150 °C. The two reactants and the polymer...
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