Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Determining the Plane of Cell Division02:13

Determining the Plane of Cell Division

4.0K
Positioning the cell division plane is a critical step during development and cell differentiation, particularly during mitosis when the plane is essential for determining the size of the two daughter cells. The cell division plane is perpendicular to the plane of chromosome segregation, but different types of organisms have different cell division mechanisms to suit their morphology and function. 
Animal cells
In animal cells, the cleavage furrow forms along the plane of cell division...
4.0K
Overview Of Cell Separation And Isolation01:20

Overview Of Cell Separation And Isolation

7.9K
Cell separation was first achieved in 1964 by S. H. Seal, who separated large tumor cells from the smaller blood cells using filtration. Two years later, Pohl and Hawk performed experiments on how cells respond differently to a nonuniform electric field based on the cell type. Such observations were the inception of cell separation methods, which allow isolating a single cell type from a heterogeneous sample.
7.9K
Separation of Sister Chromatids02:17

Separation of Sister Chromatids

4.6K
At the transition from prophase to metaphase, there is a reduction in cohesion along the chromosomal arms, resulting in the resolution of sister chromatids. However, residual cohesin connections remain to hold the sister chromatids together until the transition from metaphase to anaphase. The residual connection prevents any premature separation of sister chromatids, blocking the risks of aneuploidy within the daughter cells.
At the onset of anaphase, separase, a proteolytic enzyme, is...
4.6K
Mitosis and Cytokinesis02:03

Mitosis and Cytokinesis

283.4K
In eukaryotes, the cell division cycle is divided into distinct, coordinated cellular processes that include cell growth, DNA replication/chromosome duplication, chromosome distribution to daughter cells, and finally, cell division. The cell cycle is tightly regulated by its regulatory systems as well as extracellular signals that affect cell proliferation.
The processes of the cell cycle occur over approximately 24 hours (in typical human cells) and in two major distinguishable stages. The...
283.4K
Mitosis and Cytokinesis01:35

Mitosis and Cytokinesis

11.9K
In eukaryotes, the cell division cycle is divided into distinct, coordinated cellular processes that include cell growth, DNA replication/chromosome duplication, chromosome distribution to daughter cells, and finally, cell division. The cell cycle is tightly regulated by its regulatory systems as well as extracellular signals that affect cell proliferation.
The processes of the cell cycle occur over approximately 24 hours (in typical human cells) and in two major distinguishable stages. The...
11.9K
The Phragmoplast01:59

The Phragmoplast

6.5K
Cell division is essential for organismal growth and development. In animal cells, the central spindle and its associated proteins form the midbody, a structure that has an essential role in cytokinesis. In plants, the central spindle, along with the microtubules, actin, and other cell components, matures into the phragmoplast, which is necessary for cytokinesis. Unlike the stationary midbody, the phragmoplast expands centrifugally, eventually leading to the formation of the new cell wall.
The...
6.5K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Bis-Tetrazine Fluorogenic (Silicon)-Rhodamine Dyes for Live-Cell Labeling.

Journal of the American Chemical Society·2026
Same author

In preprints: building a resilient barrier - tissue mechanics control epithelial multilayering.

Development (Cambridge, England)·2026
Same author

3D epithelial cell topology tunes signaling range to promote precise patterning.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Direct RNA sequencing enables improved transcriptome assessment and tracking of RNA modifications for medical applications.

Nucleic acids research·2025
Same author

Differential conformational expansion of NUP98-HOXA9 oncoprotein from nanosized assemblies to macrophases.

Nature communications·2025
Same author

Pathway to Independence: a forecast for the future of developmental biology.

Development (Cambridge, England)·2025

相关实验视频

Updated: Mar 8, 2026

Label-free Isolation and Enrichment of Cells Through Contactless Dielectrophoresis
10:38

Label-free Isolation and Enrichment of Cells Through Contactless Dielectrophoresis

Published on: September 3, 2013

16.7K

揭示细胞中的分离阶段

Giulia Paci1, Edward A Lemke1

  • 1Structural and Computational Biology Unit and Cell Biology and Biophysics Unit, Meyerhofstrasse 1, 69117 Heidelberg, Germany.

Cell
|January 14, 2017
PubMed
概括

研究人员开发了一种新的光遗传工具来研究细胞中的蛋白相分离. 这种方法可以详细观察细胞组织和疾病机制,并进行精确的控制.

科学领域:

  • 细胞生物学
  • 生物物理
  • 分子生物学

背景情况:

  • 蛋白质相分离对于细胞组织至关重要.
  • 阶段分离的失调与各种疾病有关.
  • 了解分相动态对于细胞生物学来说至关重要.

研究的目的:

  • 引入一种用于研究蛋白相分离的新型光遗传工具.
  • 为了能够评估活细胞内的不同相位模式.
  • 研究这些高空间时间分辨率的模式之间的过渡路径.

主要方法:

  • 开发一种新的光遗传工具.
  • 在活细胞中应用该工具.
  • 对相隔动态的时空控制.

主要成果:

  • 该工具可以评估不同的相位模式.
  • 可以研究制度之间的过渡路径.
  • 实现了前所未有的对蛋白质相分离的时空控制.

结论:

  • 这种新的光遗传工具为研究蛋白质相分离提供了强大的方法.

更多相关视频

Cell Co-culture Patterning Using Aqueous Two-phase Systems
10:11

Cell Co-culture Patterning Using Aqueous Two-phase Systems

Published on: March 26, 2013

19.5K
Preparation of Primary Acute Lymphoblastic Leukemia Cells in Different Cell Cycle Phases by Centrifugal Elutriation
09:09

Preparation of Primary Acute Lymphoblastic Leukemia Cells in Different Cell Cycle Phases by Centrifugal Elutriation

Published on: November 10, 2017

8.9K

相关实验视频

Last Updated: Mar 8, 2026

Label-free Isolation and Enrichment of Cells Through Contactless Dielectrophoresis
10:38

Label-free Isolation and Enrichment of Cells Through Contactless Dielectrophoresis

Published on: September 3, 2013

16.7K
Cell Co-culture Patterning Using Aqueous Two-phase Systems
10:11

Cell Co-culture Patterning Using Aqueous Two-phase Systems

Published on: March 26, 2013

19.5K
Preparation of Primary Acute Lymphoblastic Leukemia Cells in Different Cell Cycle Phases by Centrifugal Elutriation
09:09

Preparation of Primary Acute Lymphoblastic Leukemia Cells in Different Cell Cycle Phases by Centrifugal Elutriation

Published on: November 10, 2017

8.9K
  • 这项技术有助于我们更好地了解细胞的组织和疾病的机制.
  • 未来的研究可以利用这种工具来探索复杂的细胞过程.