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发现抑制宿主蛋白酶的反应性微生物衍生代谢物

Chun-Jun Guo1, Fang-Yuan Chang2, Thomas P Wyche3

  • 1Department of Bioengineering and Therapeutic Sciences and California Institute for Quantitative Biosciences, University of California, San Francisco, San Francisco, CA 94158, USA.

Cell
|January 24, 2017
PubMed
概括

肠道细菌会产生抑制人类蛋白质酶的新型分子. 这项利用合成生物学的发现揭示了宿主生物学的关键微生物媒介.

关键词:
生物合成基因集群基因组学微生物组自然产品化蛋白酶抑制剂合成生物学

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