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Updated: Jul 11, 2026

Modeling Chemotherapy Resistant Leukemia In Vitro
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Published on: February 9, 2016

通过类固醇激素对全球蛋白基因表达的控制,使友性白血病细胞分化

S C Lo, R Aft, J Ross

    Cell
    |October 1, 1978
    PubMed
    概括

    像德克萨米他这样的葡萄皮质类药物抑制了分化白血病细胞中的全球蛋白基因表达,影响了mRNA和蛋白质水平. 然而,性类固醇可以增强这种基因表达,而不会影响细胞分化.

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