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Updated: Mar 8, 2026

From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028
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From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028

Published on: January 13, 2017

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聚乙烯生物合成中的聚乙烯链延长和甲基组表皮化机制和立体化学

Xinqiang Xie1, Ashish Garg1, Chaitan Khosla2

  • 1Department of Chemistry, Brown University , Box H, Providence, Rhode Island 02912-9108, United States.

Journal of the American Chemical Society
|February 4, 2017
PubMed
概括

在聚乙烯抗生素生物合成中,氧降解酶 (KR0) 域充当表皮酶. 这些域催化了 (2R) -2-甲基-3-基-ACP中间体的转化,挑战了关于它们功能的先前假设.

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Free-Radical Chain Reaction and Polymerization of Alkenes

The conversion of alkenes to macromolecules called polymers is a reaction of high commercial importance. The structure of the polymer is defined by a repeating unit, while the terminal groups are considered insignificant. The average degree of polymerization represents the number of repeating units in the polymer molecule and is denoted by the subscript n.
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Epoxidation of alkenes via oxidation with peroxy acids involves the conversion of a carbon–carbon double bond to an epoxide using the oxidizing agent meta-chloroperoxybenzoic acid, commonly known as MCPBA. Since the O–O bond of peroxy acids is very weak, the addition of electrophilic oxygen of peroxy acids to...
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Recently, the development of olefin metathesis polymerization advanced the field of polymer synthesis. Simply put, the reorganization of substituents on their double bonds between two olefins in the presence of a catalyst is known as the olefin metathesis reaction. The use of metathesis reaction for polymer synthesis is called olefin metathesis polymerization.
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Diels–Alder reactions between cyclic dienes locked in an s-cis configuration and dienophiles yield bridged bicyclic products.
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