Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Radicals: Electronic Structure and Geometry01:07

Radicals: Electronic Structure and Geometry

5.3K
This lesson delves into the geometry of a radical, which is influenced by the electronic structure of the molecule. The principle is similar to that of a lone pair, where the unpaired electron influences the geometry at the radical center.
Accordingly, the structure of a trivalent radical lies between the geometries of carbocations and carbanions. An sp2-hybridized carbocation is trigonal planar, while an sp3-hybridized carbanion is trigonal pyramidal. Here, the difference in geometry is...
5.3K
Radical Reactivity: Overview01:11

Radical Reactivity: Overview

2.9K
Radicals, the highly reactive species, gain stability by undergoing three different reactions. The first reaction involves a radical-radical coupling, in which a radical combines with another radical, forming a spin‐paired molecule. The second reaction is between a radical and a spin‐paired molecule, generating a new radical and a new spin‐paired molecule. The third reaction is radical decomposition in a unimolecular reaction, forming a new radical and a spin‐paired...
2.9K
Radical Reactivity: Electrophilic Radicals01:02

Radical Reactivity: Electrophilic Radicals

2.6K
Radicals adjacent to electron‐withdrawing groups are called electrophilic radicals. These radicals readily react with nucleophilic alkenes. For example, the malonate radical, in which the radical center is flanked by two electron‐withdrawing groups, reacts readily with butyl vinyl ether, which consists of an electron‐donating oxygen substituent. The reaction between electrophilic malonate radical and nucleophilic vinyl ether is favored because the radical has a...
2.6K
Radical Reactivity: Steric Effects01:10

Radical Reactivity: Steric Effects

2.6K
The presence of electron-donating, electron-withdrawing, or conjugating groups adjacent to a radical center, imparts electronic stabilization to the radicals. Examples of such electronically-stabilized radicals are triphenylmethyl, tetramethylpiperidine‐N‐oxide, and 2,2‐diphenyl‐1‐picrylhydrazyl. These radicals are remarkably stable and are known as persistent radicals. Some of the persistent radicals can even be isolated and purified.
Along with electronic...
2.6K
Radical Reactivity: Nucleophilic Radicals01:16

Radical Reactivity: Nucleophilic Radicals

2.7K
Radicals adjacent to electron-donating groups are called nucleophilic radicals. These radicals readily react with electrophilic alkenes. The SOMO–LUMO interactions are the driving force for the reaction, where the high-energy SOMO of the electron-rich, nucleophilic radicals interacts with the low-energy LUMO of the electron-deficient, electrophilic alkenes. Such SOMO–LUMO interactions are the basis of reactive radical traps, affecting the selectivity in radical reactions. For...
2.7K
Radical Anti-Markovnikov Addition to Alkenes: Overview01:25

Radical Anti-Markovnikov Addition to Alkenes: Overview

4.3K
The addition of hydrogen bromide to alkenes in the presence of hydroperoxides or peroxides proceeds via an anti-Markovnikov pathway and yields alkyl bromides.
4.3K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Effect of Precompression on Detonation Performance and Products of Energetic Materials: Application to CL-20.

The journal of physical chemistry. C, Nanomaterials and interfaces·2026
Same author

Cationic carbon nanotube modulates surface fields for general acidic CO<sub>2</sub> reduction with aqueous organic cations.

Nature communications·2026
Same author

Publisher Correction: Ultralow-voltage electrochemical organic light-emitting transistors with pinned and wide lateral recombination.

Nature materials·2026
Same author

The mechanism for ligand activation of the Smoothened G protein-coupled receptor.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Modified Surgical Technique Combined with Radiation Therapy for Keloid Management.

Aesthetic plastic surgery·2026
Same author

Ultralow-voltage electrochemical organic light-emitting transistors with pinned and wide lateral recombination.

Nature materials·2026

相关实验视频

Updated: Mar 7, 2026

Free Radicals in Chemical Biology: from Chemical Behavior to Biomarker Development
14:22

Free Radicals in Chemical Biology: from Chemical Behavior to Biomarker Development

Published on: April 15, 2013

20.8K

尺寸匹配的基数多价值

Mark C Lipke1, Tao Cheng2, Yilei Wu1

  • 1Department of Chemistry, Northwestern University , 2145 Sheridan Road, Evanston, Illinois 60208, United States.

Journal of the American Chemical Society
|February 8, 2017
PubMed
概括
此摘要是机器生成的。

研究人员开发了一种新的分子方形宿主,通过激素配对相互作用选择性地结合特定的二基旋客. 这创造了一个稳定的四根复合体,在超分子化学中推进分子识别.

更多相关视频

Isolating Free Carbenes, their Mixed Dimers and Organic Radicals
10:44

Isolating Free Carbenes, their Mixed Dimers and Organic Radicals

Published on: April 19, 2019

11.8K
Following the Dynamics of Structural Variants in Experimentally Evolved Populations
04:52

Following the Dynamics of Structural Variants in Experimentally Evolved Populations

Published on: February 3, 2023

1.4K

相关实验视频

Last Updated: Mar 7, 2026

Free Radicals in Chemical Biology: from Chemical Behavior to Biomarker Development
14:22

Free Radicals in Chemical Biology: from Chemical Behavior to Biomarker Development

Published on: April 15, 2013

20.8K
Isolating Free Carbenes, their Mixed Dimers and Organic Radicals
10:44

Isolating Free Carbenes, their Mixed Dimers and Organic Radicals

Published on: April 19, 2019

11.8K
Following the Dynamics of Structural Variants in Experimentally Evolved Populations
04:52

Following the Dynamics of Structural Variants in Experimentally Evolved Populations

Published on: February 3, 2023

1.4K

科学领域:

  • 超分子化学
  • 材料科学
  • 有机化学

背景情况:

  • 持久的π-基,如甲基基 (MV+•),表现出弱的基-基相互作用.
  • 这些相互作用是超分子化学的关键,能够形成稳定的宿主-客体复合体.
  • 之前的工作确立了MV+•和环主体[cyclobis(paraquat-p-phenylene) ]2(+•) (CBPQT2(+•)之间的强烈复合.

研究的目的:

  • 为了将基因配对的分子识别扩展到一个更大的,方形的基因主体,[cyclobis{(paraquat-4,4'-biphenylene) ] (MS{2}+•)
  • 评估与MS2(+•)的同位素二基旋客的结合.
  • 描述由此产生的四根复合体,并了解其稳定性的因素.

主要方法:

  • 监测复合形成和结合亲和力的UV-Vis-NIR光谱.
  • 定位实验和可变温度光谱 (UV-Vis-NIR,EPR) 用于确定热力学参数.
  • 单晶X射线衍射和密度功能理论 (DFT) 计算用于结构分析.
  • 循环电压测量检测复合物的电子性质.

主要成果:

  • MSm-CBPQT选择性地结合与甲基烯结合的二基旋 (m-CBPQT),形成一个四基复合物[MSm-CBPQT].
  • 结合是由有利的变化驱动的,尽管被罚抵消,导致与较小系统可比的关联常数 (Ka = (1.12 ± 0.08) × 105 M-1).
  • 结构分析显示m-CBPQT是MS的理想尺寸,并且该复合物破坏了晶体结构中的典型扩展基配对.
  • 循环电压测量证实了复合体内的基态的稳定.

结论:

  • 这项研究成功地证明了激素配对分子识别的扩展到一个更大的方形宿主.
  • m-CBPQT的理想尺寸和电子特性使其在MS中具有强大的结合性.
  • 这些发现为设计基于激素相互作用的新型超分子组件提供了洞察力.