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EPRS 是一种影响小鼠脂肪的关键mTORC1-S6K1效应体

Abul Arif1, Fulvia Terenzi1, Alka A Potdar2

  • 1Department of Cellular and Molecular Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA.

Nature
|February 9, 2017
PubMed
概括

科学家发现谷氨酸-基-tRNA合成酶 (EPRS) 是肥胖和衰老的关键因素,由mTORC1-S6K1途径调节. 它的酸化控制脂肪代谢和寿命.

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