Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Metastasis02:30

Metastasis

6.7K
Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
6.7K
Cancer Stem Cells and Tumor Maintenance02:40

Cancer Stem Cells and Tumor Maintenance

6.2K
Early diagnosis and treatment can often cure cancer. However, even with treatment, residual cells called cancer stem cells (CSC) might remain, often causing tumor recurrence. These cancer stem cells possess the potential for self-renewal and multi-lineage differentiation and are often responsible for the therapeutic resistance displayed in most cancers.
Cancer stem cells are thought to originate from tissue-specific normal stem cells or progenitor cells. The normal stem cells usually reside in...
6.2K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Cediranib with weekly paclitaxel or olaparib versus weekly paclitaxel for advanced or recurrent endometrial cancer (COPELIA): a multicentre, open-label, randomised, phase 2 trial in the UK.

EClinicalMedicine·2026
Same author

Advancing the applications of liquid biopsies in oncology.

Nature reviews. Genetics·2026
Same author

Use of circulating tumour DNA to prospectively guide a switch from targeted to immune therapy in BRAF mutant advanced melanoma: the randomised phase II CAcTUS trial.

Nature communications·2026
Same author

Cell-free DNA methylome and fragmentome analysis for relapse monitoring of Ewing sarcoma.

EMBO molecular medicine·2026
Same author

Abrogation of Oncogenic RAS Signaling by a RAS(ON) Inhibitor Doublet Primes Immune-Refractory KRASG12C-Mutant NSCLC for Immune Checkpoint Blockade.

Cancer discovery·2026
Same author

Expression of Concern: Application of Sequencing, Liquid Biopsies, and Patient-Derived Xenografts for Personalized Medicine in Melanoma.

Cancer discovery·2026

相关实验视频

Updated: Mar 7, 2026

Rapid Isolation of Viable Circulating Tumor Cells from Patient Blood Samples
07:32

Rapid Isolation of Viable Circulating Tumor Cells from Patient Blood Samples

Published on: June 15, 2012

27.3K

快照:循环中的瘤细胞

Caroline Dive1, Ged Brady1

  • 1Cancer Research UK Manchester Institute, University of Manchester, Manchester M20 4BX, UK.

Cell
|February 11, 2017
PubMed
概括

循环瘤细胞 (CTC) 表示癌症存在和转移风险. 先进的技术使得癌症生物学洞察力和新的血液生物标志物的CTC分析成为可能.

科学领域:

  • 癌症学
  • 分子生物学
  • 生物标志物发现

背景情况:

  • 在癌症患者的血液中存在循环瘤细胞 (CTC).
  • CTCs表明了原发性瘤的存在和转移的可能性.
  • 分析CTC可以了解癌症的进展和治疗反应.

研究的目的:

  • 强调CTC作为癌症和转移的指标的重要性.
  • 讨论技术进步在CTC隔离和分析中的作用.
  • 探索CTC在开发新的基于血液的癌症生物标志物的潜力.

主要方法:

  • 审查CTC隔离技术的最新技术发展.
  • 对从CTC中获得的生物见解的研究分析.
  • 探索CTC在生物标志物开发中的当前和未来应用.

主要成果:

  • CTC 作为瘤检测和转移潜力的关键指标.
  • 技术进步可以更有效地隔离和描述CTC.
  • CTC分析提供了有关癌症生物学,治疗疗效和耐药性机制的宝贵数据.

结论:

更多相关视频

Capture and Release of Viable Circulating Tumor Cells from Blood
08:10

Capture and Release of Viable Circulating Tumor Cells from Blood

Published on: October 28, 2016

9.0K
Circulating Tumor Cell Lines: an Innovative Tool for Fundamental and Translational Research
07:47

Circulating Tumor Cell Lines: an Innovative Tool for Fundamental and Translational Research

Published on: December 25, 2021

4.7K

相关实验视频

Last Updated: Mar 7, 2026

Rapid Isolation of Viable Circulating Tumor Cells from Patient Blood Samples
07:32

Rapid Isolation of Viable Circulating Tumor Cells from Patient Blood Samples

Published on: June 15, 2012

27.3K
Capture and Release of Viable Circulating Tumor Cells from Blood
08:10

Capture and Release of Viable Circulating Tumor Cells from Blood

Published on: October 28, 2016

9.0K
Circulating Tumor Cell Lines: an Innovative Tool for Fundamental and Translational Research
07:47

Circulating Tumor Cell Lines: an Innovative Tool for Fundamental and Translational Research

Published on: December 25, 2021

4.7K
  • 循环瘤细胞对于了解癌症的传播和患者的预后至关重要.
  • 在CTC分析的进步开辟了新的诊断和治疗监测途径.
  • 在瘤学中,CTC 是一个有前途的血液生物标志物开发领域.