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来自脂肪的循环miRNAs调节其他组织中的基因表达

Thomas Thomou1, Marcelo A Mori2, Jonathan M Dreyfuss3,4

  • 1Section on Integrative Physiology &Metabolism, Joslin Diabetes Center and Harvard Medical School, Boston, Massachusetts, USA.

Nature
|February 16, 2017
PubMed
概括

脂肪组织释放出调节新陈代谢的外体微RNA (miRNA). 在小鼠中恢复脂肪组织改善了葡萄糖耐受性,降低了FGF21,表明外体miRNA作为新型脂肪素.

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