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HSP90影响人类遗传变异的后果

Georgios I Karras1, Song Yi2, Nidhi Sahni2

  • 1Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA.

Cell
|February 21, 2017
PubMed
概括

热冲击蛋白90 (HSP90) 通过调节突变蛋白的功能来影响人类遗传疾病的严重程度. 增加的HSP90结合与较轻的症状相关,为疾病变异提供了洞察力.

关键词:
芬科尼贫血症HSP70 的情况HSP90缓冲系统癌症基因与环境的相互作用

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