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Updated: Mar 7, 2026

In Vivo Modeling of the Morbid Human Genome using Danio rerio
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仅限于人类早期发育的生物 CNV 突变型

Pengfei Liu1, Bo Yuan2, Claudia M B Carvalho2

  • 1Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Baylor Genetics, Houston, TX 77021, USA.

Cell
|February 25, 2017
PubMed
概括

一项新的研究揭示了基因组疾病患者的多重de novo拷贝数变异 (dnCNV) 现象. 这表明在早期发育过程中存在过渡性"CNV突变状态",为遗传条件和癌症生物学提供了洞察力.

关键词:
其他国家/地区进行DNA复制癌症在新复制基因组不稳定性细菌系变种者

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