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Retroviral Infection of Murine Embryonic Stem Cell Derived Embryoid Body Cells for Analysis of Hematopoietic Differentiation
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斯皮-1 是病毒诱导的小鼠红血球白血病中的假定瘤基因

F Moreau-Gachelin1, A Tavitian, P Tambourin

  • 1INSERM U-248, Faculté de Médecine Lariboisière-Saint Louis, Paris, France.

Nature
|January 21, 1988
PubMed
概括

复原病毒插入性突变发生可以激活瘤基因. 研究人员发现了一种新的瘤基因Spi-1,它在由脏聚焦形成病毒 (SFFV) 诱导的小鼠红血球白血病中经常被重新排列,这表明它在这种癌症中的作用.

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