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T细胞共刺激受体CD28是PD-1介导抑制的主要点

Enfu Hui1, Jeanne Cheung2, Jing Zhu2

  • 1Department of Cellular and Molecular Pharmacology and the Howard Hughes Medical Institute, University of California, San Francisco, CA 94158, USA.

Science (New York, N.Y.)
|March 11, 2017
PubMed
概括

编程细胞死亡-1 (PD-1) 通过脱化CD28共受体而不是T细胞受体 (TCR) 来抑制T细胞激活. 这显示了PD-1

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