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A Method to Study de novo Formation of Chromatin Domains
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聚合物抑制的染色体的传播需要对DNA进行序列特定的招募

Friederike Laprell1, Katja Finkl1, Jürg Müller2

  • 1Laboratory of Chromatin Biology, Max Planck Institute of Biochemistry, Am Klopferspitz 18, 82152 Martinsried, Germany.

Science (New York, N.Y.)
|March 18, 2017
PubMed
概括

聚抑制复合体2 (PRC2) 使用基因标记 (H3K27me3) 来维持基因抑制. 这种表观遗传记忆是通过DNA复制稀释的,但在停滞的细胞中仍然存在,显示出序列独立的遗传.

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