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CRISPR-Cas系统利用病毒DNA注射来建立和维持适应性免疫力

Joshua W Modell1, Wenyan Jiang1, Luciano A Marraffini1

  • 1Laboratory of Bacteriology, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA.

Nature
|March 30, 2017
PubMed
概括

在感染过程中,集群定期间隔的短平行列重复 (CRISPR) - Cas 系统从入侵的菌体中获得新的DNA间隔器. 这种及时获取,特别是从早期注射的DNA中获取,增强了细菌对病毒威胁的免疫力.

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