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Updated: May 5, 2026

Synthesis of Protein Bioconjugates via Cysteine-maleimide Chemistry
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通过迈克尔添加到5-甲基 Pyrrolones 进行特异性和无痕可移除的生物结合

Yingqian Zhang1, Xiaoping Zhou1, Yonghui Xie1

  • 1State Key Laboratory of Elemento-Organic Chemistry and Department of Chemical Biology, College of Chemistry, Nankai University , Tianjin 300071, China.

Journal of the American Chemical Society
|April 14, 2017
PubMed
概括

五甲基罗 (5MPs) 提供稳定,特定的生物结合,可控制货物的释放和提保护. 这些工具很容易合成,在生理条件下优于maleimides.

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