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Updated: May 3, 2026

Profiling of Methyltransferases and Other S-adenosyl-L-homocysteine-binding Proteins by Capture Compound Mass Spectrometry CCMS
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从trans-AT多基基合成酶中阐明C-甲基转移酶的立体特异性

Xinqiang Xie1, Chaitan Khosla2, David E Cane1

  • 1Department of Chemistry, Brown University , Box H, Providence, Rhode Island 02912-9108, United States.

Journal of the American Chemical Society
|April 22, 2017
PubMed
概括

在细菌聚基合成中,S-Adenosyl甲胺 (SAM) 依赖的C-甲基转移酶催化了关键的C2-甲基化. 这项研究表明,这些酶只能产生2-甲基-3-基-ACP中间体的 (2R) 立体同位素.

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