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Updated: Mar 3, 2026

Measuring G-protein-coupled Receptor Signaling via Radio-labeled GTP Binding
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具有GRK5的β2-上腺素受体复合物的结构和功能分析

Konstantin E Komolov1, Yang Du2, Nguyen Minh Duc3

  • 1Department of Biochemistry and Molecular Biology and the Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA.

Cell
|April 22, 2017
PubMed
概括

研究人员阐明了与β-2上腺素受体 (β2AR) 相互作用的G蛋白结合受体激酶5 (GRK5) 的分子机制. 这项研究揭示了对调节GPCR信号的动态复合形成和构造变化.

关键词:
G蛋白结合受体与G蛋白结合的受体激酶交叉链接质谱学分子动力学化乙氨基受体

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