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Updated: Mar 3, 2026

Analyses of Mitochondrial Calcium Influx in Isolated Mitochondria and Cultured Cells
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Published on: April 27, 2018

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线粒体Na+/Ca2+交换器对于Ca2+的稳态和生存能力至关重要

Timothy S Luongo1, Jonathan P Lambert1, Polina Gross2

  • 1Center for Translational Medicine, Department of Pharmacology, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA.

Nature
|April 27, 2017
PubMed
概括

在小鼠心脏中删除线粒体出口器NCLX (Slc8b1) 导致严重心力衰竭和突然死亡. 恢复NCLX功能,防止心脏损伤,突出其在心脏健康中的关键作用.

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