运动员一生运动量与冠状动脉样硬化的关系
Vincent L Aengevaeren1, Arend Mosterd2, Thijs L Braber2
1From Departments of Physiology (V.L.A., T.M.H.E.) and Cardiology (V.L.A.), Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, the Netherlands; Department of Cardiology, Meander Medical Center, Amersfoort, the Netherlands (A.M., T.L.B.); Department of Radiology (T.L.B., B.K.V.), Department of Cardiology (P.A.D.), and Julius Center for Health Sciences and Primary Care (D.E.G.), University Medical Center Utrecht, the Netherlands; Department of Radiology, University Medical Center Groningen, the Netherlands (N.H.J.P.); Netherlands Heart Institute, Utrecht, the Netherlands (P.A.D.); Division of Cardiology, Hartford Hospital, CT (P.D.T.); and Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, United Kingdom (T.M.H.E.). vincent.aengevaeren@radboudumc.nl thijs.eijsvogels@radboudumc.nl.
高度的终身运动量 (>2000MET分钟/周) 与中年男性的冠状动脉结石化 (CAC) 和斑块增加有关. 然而,最活跃的运动员表现出更良性的斑块组成, 这可能解释了他们的寿命.
科学领域:
- 心脏病学
- 运动生理学
- 放射学
背景情况:
- 较高的体力活动与心血管疾病风险降低有关.
- 关于运动剂量反应和高体积冠状动脉样硬化的潜在加速存在争议.
- 终身运动与冠状动脉硬化之间的关系需要进一步研究.
研究的目的:
- 确定中年男性终身运动量与冠状动脉硬化之间的关联.
- 调查高运动量是否会加速冠状动脉样硬化.
- 探索冠状动脉硬化斑块与运动量相关的特征.
主要方法:
- 284名中年男性运动员接受了冠状动脉化 (CAC) 和斑块评估的计算机断层扫描 (CT).
- 用每周代谢等价任务 (MET) 分钟记录和量化终身运动史.
- 参与者被分为运动量小组:<1000,1000-2000和>2000MET-min/week.
主要成果:
- 与运动量<1000MET-min/week的男性相比,运动量>2000MET-min/week的男性的CAC分数和患病率显著更高.
- 非常强烈的运动 (≥9MET) 与CAC和斑块的患病率增加有关.
- 在CAC患者中,斑块特征在运动量组之间没有显著差异.
- 与最不活跃的组相比,最活跃的组 (>2000 MET-min/week) 的混合斑块较少,化斑块较多.
结论:
- 较高的终身运动量与冠状动脉样硬化 (CAC和斑块) 的患病率增加有关.
- 尽管斑块发病率较高,但最活跃的运动员 (> 2000 MET-min/week) 的斑块组成较为良性 (混合斑块较少,化斑块较多).
- 这些发现可能有助于解释耐力运动员的长寿,尽管冠状动脉斑块负担增加.
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