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调节巨细胞中的胆固醇运输

Petteri Rinne1, Martina Rami2, Salla Nuutinen2

  • 1From Institute for Cardiovascular Prevention, Ludwig-Maximilians-University Munich, Germany (P.R., M.R., D.S., E.P.C.v.d.V., R.Q.-P., L.R., C.W., S.S.); Department of Pharmacology, Drug Development and Therapeutics, University of Turku and Turku University Hospital, Finland (P.R., S.N.); Department of Clinical Chemistry, Fimlab Laboratories and Finnish Cardiovascular Research Center, Tampere, Faculty of Medicine and Life Sciences, University of Tampere (L.-P.L., E.R., N.O., T.L.); Department of Surgery, Tampere University Hospital, Finland (N.O.); Department of Chemistry and Biochemistry, University of Arizona, Tucson (M.C., V.J.H.); and German Centre for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany (C.W., S.S.). pperin@utu.fi.

Circulation
|April 29, 2017
PubMed
概括

通过减少胆固醇的吸收和促进巨细胞的排放,激活梅拉诺科林1受体 (MC1- R) 保护动脉样硬化. 这种双重作用防止泡细胞的形成,并增强斑块的稳定性.

关键词:
动脉样硬化胆固醇炎症的发生巨细胞

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