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Updated: Mar 3, 2026

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金属离子有效地消除了神经毒素A的作用

Paul T Bremer1, Sabine Pellett2, James P Carolan3

  • 1Departments of Chemistry and Immunology, The Skaggs Institute for Chemical Biology, Worm Institute of Research and Medicine (WIRM), The Scripps Research Institute , 10550 North Torrey Pines Road, La Jolla, California 92037, United States.

Journal of the American Chemical Society
|May 6, 2017
PubMed
概括

研究人员发现某些金属离子,如铜和,可以抑制肉毒神经毒素血清型A (BoNT/A) 蛋白酶. 基于金属的药物复合物在细胞和动物模型中显示出对抗BoNT/A效应的潜力,提供了一种新的治疗策略.

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