甲状腺癌查:美国预防服务工作组建议声明
, Kirsten Bibbins-Domingo1, David C Grossman2
1University of California, San Francisco.
JAMA
|May 12, 2017
概括
美国预防服务工作组 (USPSTF) 建议不对无症状成年人进行甲状腺癌查. 证据表明甲状腺癌查的潜在危害超过了益处.
科学领域:
- 内分泌学
- 癌症学
- 预防医学
背景情况:
- 甲状腺癌的发病率显著上升,
- 大多数甲状腺癌的预后很好,
研究的目的:
- 更新美国预防服务工作组 (USPSTF) 关于甲状腺癌查的建议.
- 评估无症状成年人查甲状腺癌的益处和危害.
主要方法:
- 对查益处和危害的证据进行系统审查.
- 评估部触摸和超声波等查方法的诊断准确性.
- 对查检测到的甲状腺癌治疗结果的评估.
主要成果:
- 没有足够的直接证据证明查有好处;整体好处可能很小.
- 从查和治疗中产生的中度至重大危害,包括过度诊断和过度治疗.
- 甲状腺癌查的净益被确定为负.
结论:
- 在无症状的成年人中,USPSTF建议不要进行甲状腺癌查.
- 查和后续治疗的潜在危害可能超过任何潜在益处.
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