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Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes
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通过多价值诱导的绑定单元对Telomeric G-Quadruplexes进行适应性和特定的识别

Jibin Abraham Punnoose1, Yue Ma2, Yuanyuan Li1

  • 1Department of Chemistry and Biochemistry, Kent State University , Kent, Ohio 44242, United States.

Journal of the American Chemical Society
|May 16, 2017
PubMed
概括

研究人员开发了一种多价性策略,专门针对多个DNAG四重复. 一种端美四聚合物与多聚合物G四聚合物结合的强度是单聚合物结合的40倍以上.

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