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在骨髓白血病中通过重新编程的BCAA代谢导致癌症的进展

Ayuna Hattori1,2, Makoto Tsunoda3, Takaaki Konuma4

  • 1Department of Biochemistry and Molecular Biology, Franklin College of Arts and Sciences, The University of Georgia, Athens, Georgia 30602, USA.

Nature
|May 18, 2017
PubMed
概括

由BCAT1调节的分支链氨基酸 (BCAA) 代谢驱动慢性髓性白血病 (CML) 的进展. 针对MSI2-BCAT1途径为髓性白血病提供了一种新的治疗策略.

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