通过红细胞入侵受体的结构变异对疟疾的抵抗

Ellen M Leffler1,2, Gavin Band1,2, George B J Busby1

  • 1Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.

Science (New York, N.Y.)
|May 20, 2017
PubMed
概括

红细胞基因的基因变异,如GYPA和GYPB,会影响Plasmodium falciparum的入侵. 一种特定的结构变异,丹图抗原,可显著降低40%的严重疟疾风险.