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Rapid In Vivo Fixation and Isolation of Translational Complexes from Eukaryotic Cells
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整体冷电磁场阐明了翻译准确性的机制

Anna B Loveland1, Gabriel Demo1, Nikolaus Grigorieff2

  • 1RNA Therapeutics Institute, Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, 368 Plantation Street, Worcester, Massachusetts 01605, USA.

Nature
|May 25, 2017
PubMed
概括

精确的基因翻译依赖于核糖体的精确mRNA解码. 这项研究揭示了核糖体如何区分正确的 (同源) 和不正确的 (近同源) 转移RNA的结构机制,确保了忠实的蛋白质合成.

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