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Updated: Mar 1, 2026

Experimental Infection with Listeria monocytogenes as a Model for Studying Host Interferon-γ Responses
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Published on: November 16, 2016

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干扰素-γ驱动Treg脆弱性以促进抗瘤免疫力

Abigail E Overacre-Delgoffe1, Maria Chikina2, Rebekah E Dadey3

  • 1Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

Cell
|May 30, 2017
PubMed
概括

调节性T细胞 (Tregs) 阻碍抗瘤免疫力. 由于Neuropilin-1缺乏Tregs的干扰素,它们的脆弱性提高了瘤清除和免疫治疗反应.

关键词:
美国癌症免疫疗法干扰素-γ干扰素-γ受体神经蛋白-1监管T细胞瘤免疫学瘤微环境

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