在患有囊性纤维化症的成年人中,缺乏和可能增加癌症的风险
Lancet (London, England)
|October 19, 1985
概括
患有囊性纤维化 (CF) 的年轻人通常具有低和维生素E水平. 这些缺陷可能会增加癌症风险,特别是在老年CF患者中.
科学领域:
- 生物化学 生物化学
- 在瘤学瘤学.
- 肺部病理学 肺部病理学
背景情况:
- 囊性纤维化 (CF) 是一种影响多个器官的遗传性疾病.
- 在CF患者中,营养缺乏是常见的.
- 氧化应激和炎症与CF病变发生有关.
研究的目的:
- 在患有CF的年轻成年人中研究血清和维生素E度.
- 探索这些微量营养素与CF癌症风险之间的关联.
主要方法:
- 从20名患有CF的年轻成年人收集了血液样本.
- 测量了和维生素E的血清度.
- 在队列中注意到癌症发病率.
主要成果:
- 在大多数参与者中观察到低血清度.
- 低血清维生素E度也很普遍.
- 两个患有CF的参与者被诊断出患有癌症.
结论:
- 低循环水平可能与CF患者癌症风险增加有关.
- 降低维生素E水平可能会加剧这种风险.
- 患有CF的老年人可能是患癌症的高风险群体.
更多相关视频
06:46Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
Published on: September 27, 2024
05:56Implementation of Non-invasive Point of Care Transient Elastography for Evaluation of Liver Disease in Pediatric Populations with Cystic Fibrosis
Published on: August 29, 2025
相关概念视频
Cancer Prevention
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
Cystic Fibrosis: Pathogenesis
Cystic fibrosis (CF), an autosomal recessive disorder, significantly affects the function of exocrine glands. This genetically inherited disease is characterized by the production of thick and sticky mucus, which can severely affect various organs and systems in the body.
CF is primarily caused by a genetic mutation in a chromosome 7 gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The most common gene mutation leading to CF is the ΔF508 mutation, but...
CF is primarily caused by a genetic mutation in a chromosome 7 gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The most common gene mutation leading to CF is the ΔF508 mutation, but...
Vitamins
Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced in our...
Psychoneuroimmunology: Diabetes and Cancer
Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
