前列腺癌的诊断和治疗:一个回顾
1Department of Urology, David Geffen School of Medicine, University of California, Los Angeles2Department of Health Policy and Management, Fielding School of Public Health, University of California, Los Angeles3School of Nursing, University of California, Los Angeles.
JAMA
|June 28, 2017
概括
在前列腺癌的诊断和治疗方面取得的进展使得个性化护理成为可能. 新的化疗和向治疗改善了转移性疾病的存活率,为患者提供了更好的结果.
科学领域:
- 癌症学
- 尿道瘤学
背景情况:
- 前列腺癌是男性癌症死亡的主要原因.
- 准确的诊断和风险分层对于有效的管理至关重要.
研究的目的:
- 审查前列腺癌诊断和治疗的最新进展.
- 突出改善患者分层和治疗选择.
主要方法:
- 对包括成像和生物标志物在内的诊断进步进行审查.
- 分析局部化和转移性疾病的治疗策略.
- 对晚期前列腺癌的新疗法进行评估.
主要成果:
- 改善风险分层使得个性化治疗建议成为可能.
- 积极监测是低风险前列腺癌的安全选择.
- 与单独的抗雄激素治疗相比,化疗改善了转移性疾病的存活率.
- 新药在对激素耐药的转移性前列腺癌中显示出有效性.
结论:
- 在诊断和治疗方面取得的进展有助于改善前列腺癌患者的治疗.
- 治疗决策越来越依赖于预后和患者的偏好.
- 新型疗法可以改善晚期前列腺癌的治疗效果.
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