大米中转录因子的自然基因赋予了广谱抗爆
Weitao Li1, Ziwei Zhu1, Mawsheng Chern2
1State Key Laboratory of Hybrid Rice, Key Laboratory of Major Crop Diseases and Collaborative Innovation Center for Hybrid Rice in Yangtze River Basin, Rice Research Institute, Sichuan Agricultural University at Wenjiang, Chengdu, Sichuan 611130, China.
Cell
|July 1, 2017
概括
科学家发现一种天然的基因变异, 这一发现存在于10%的品种中,为提高作物弹性和减少产量损失提供了一种策略.
科学领域:
- 植物病理学
- 遗传学
- 农业科学
背景情况:
- 米爆发是由Magnaporthe oryzae引起的,对全球粮食安全构成重大威胁,造成大量的作物损失.
- 非种族特异性耐药性比种族特异性耐药性更好,因为它具有更广泛的抗病原体和耐久性.
研究的目的:
- 鉴定导致非种族特异性抗米爆的遗传因素.
- 探索一种新发现的自然等位基因在米中产生持久性抗病能力的潜力.
主要方法:
- 全基因组关联研究 (GWAS) 以确定耐药性基因.
- 对3000个被测序的米基因组进行分析以确定基因组的频率.
- 基因表达和调节机制的分子分析.
主要成果:
- 鉴定出一种C2H2型转录因子的自然等位基因,使其具有非种族特异性的抗米爆发性.
- 这种有利的等位基因存在于约10%的米基因组中,这表明在繁殖过程中进行了选择.
- 通过影响MYB转录因子结合,抑制H2O2降解和增强耐药性,该等位基因导致bsr- d1基因表达的减少.
结论:
- 一个新型的等位基因提供了一种策略,用于在米中培养对爆发性疾病的持久抵抗力.
- 了解这种基因的调节机制可以指导未来的作物改进工作.
- 该等位基因的流行表明其在农业实践中的实用性和选择性.
相关概念视频
Plant Breeding and Biotechnology
22.0K
Crop cultivation has a long history in human civilization, with records showing the cultivation of cereal plants beginning at around 8000 BC. This early plant breeding was developed primarily to provide a steady supply of food.
22.0K
Cell Signaling in Plants
6.8K
Plant cells communicate to coordinate their cycle of growth, flowering and fruiting, and activities in roots, shoots, and leaves in response to the changing environmental conditions. Plant signaling is distinct from animal signaling. Plants primarily utilize enzyme-linked receptors, whereas the largest class of cell-surface receptors in animals are G-protein coupled receptors (GPCRs). Unlike animals, receptor tyrosine kinases are rare in plants. Instead, plants have a diverse class of...
6.8K
Transgenic Plants
8.8K
Recombinant DNA technology called transgenesis is often used to add a foreign gene or remove a detrimental gene from an organism. Such genetically modified organisms are called transgenic organisms.
The first-ever transgenic plant was a tobacco plant developed in 1983 that showed resistance against the tobacco mosaic virus. Since then, many transgenic plants have been developed and commercialized for improving the agricultural, ornamental, and horticultural value of a crop plant. Transgenic...
The first-ever transgenic plant was a tobacco plant developed in 1983 that showed resistance against the tobacco mosaic virus. Since then, many transgenic plants have been developed and commercialized for improving the agricultural, ornamental, and horticultural value of a crop plant. Transgenic...
8.8K
Overview of Transposition and Recombination
19.7K
Transposons make up a significant part of genomes of various organisms. Therefore, it is believed that transposition played a major evolutionary role in speciation by changing genome sizes and modifying gene expression patterns. For example, in bacteria, transposition can lead to conferring antibiotic resistance. Movement of transposable elements within the genetic pool of pathogenic bacteria can aid in transfer of antibiotic-resistant genetic elements. In eukaryotes, transposons can carry out...
19.7K
General Transcription Factors
7.3K
Tissue-specific transcription factors contribute to diverse cellular functions in mammals. For example, the gene for beta globin, a major component of hemoglobin, is present in all cells of the body. However, it is only expressed in red blood cells because the transcription factors that can bind to the promoter sequences of the beta globin gene are only expressed in these cells. Tissue-specific transcription factors also ensure that mutations in these factors may impair only the function of...
7.3K
Transduction
2.1K
Among the three main modes of HGT—transformation, conjugation, and transduction—transduction is unique in that it is mediated by bacteriophages, or bacterial viruses.Transduction occurs in two ways. Generalized transduction occurs during the lytic cycle of a bacteriophage infection. In this process, bacteriophages infect bacterial cells, replicate within them, and ultimately cause cell lysis, releasing newly assembled virions. Occasionally, random fragments of the bacterial genome...
2.1K


