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Updated: May 7, 2026

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在下一代测序芯片上对CRISPR-Cas复合体进行大规模并行生物物理分析

Cheulhee Jung1, John A Hawkins2, Stephen K Jones1

  • 1Department of Molecular Biosciences and Institute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, TX 78712, USA.

Cell
|July 1, 2017
PubMed
概括

我们开发了一种名为CHAMP的新方法, 用以绘制数百万个DNA序列的CRISPR-Cas蛋白相互作用. 这揭示了CRISPR-Cas复合体如何与非目标DNA结合,改善了我们对基因编辑特异性的理解.

关键词:
关于CRISPR的研究其他国家连续发生生物物理光显微镜下一代测序

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