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Updated: May 10, 2026

Synthesis of Protein Bioconjugates via Cysteine-maleimide Chemistry
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通过高效的特定位置生物结合实现机械不稳定的α-螺旋蛋白的快速表征

Robert Walder1, Marc-André LeBlanc, William J Van Patten1

  • 1JILA, National Institute of Standards and Technology and University of Colorado , Boulder, Colorado 80309, United States.

Journal of the American Chemical Society
|July 6, 2017
PubMed
概括

本研究提出了原子力显微镜 (AFM) 单分子力光谱 (SMFS) 的新方法,该方法显著提高了数据质量和吞吐量. 这种增强的技术可以快速描述各种生物分子的机械性质,包括机械不稳定的α3D蛋白.

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