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癌细胞耐治疗状态与脂质过氧化酶通路的依赖性

Vasanthi S Viswanathan1, Matthew J Ryan1, Harshil D Dhruv2

  • 1Broad Institute, 415 Main Street, Cambridge, Massachusetts 02142, USA.

Nature
|July 6, 2017
PubMed
概括

癌细胞通过高酶状态发展耐药性,这种状态依赖脂质过氧化酶途径来逃避铁亡. 抑制这种途径使得抗癌细胞易受细胞死亡的影响.

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