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相关概念视频

Infection01:20

Infection

13.0K
When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
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Stages of Infection01:26

Stages of Infection

65.9K
Stages of infection describe what happens to a susceptible host once a pathogen invades the human body. The stages of infection are incubation, prodromal, illness, stage of decline, and convalescence. The incubation stage is the period from exposure to a pathogen until symptoms start. The infected person is unaware of impending illness as the pathogens grow and multiply within the body. The duration may vary depending on the type of infection. The incubation period of measles averages ten to...
65.9K
Steps in Outbreak Investigation01:18

Steps in Outbreak Investigation

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In the ever-evolving field of public health, statistical analysis serves as a cornerstone for understanding and managing disease outbreaks. By leveraging various statistical tools, health professionals can predict potential outbreaks, analyze ongoing situations, and devise effective responses to mitigate impact. For that to happen, there are a few possible stages of the analysis:
639
Models of Health Promotion and Illness Prevention II01:18

Models of Health Promotion and Illness Prevention II

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The person's health status fluctuates continually, varying from being in good health to becoming ill and returning to being healthy. To understand the concept of illness prevention, there are two models. First, the health-illness continuum model is a graphic representation of an individual's wellness. It states that a person is considered healthy in the absence of physical disease and the presence of good emotional health.
The agent-host-environment model states that disease results...
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Prevalence and Incidence01:08

Prevalence and Incidence

2.1K
In statistical epidemiology and health sciences, two essential metrics—prevalence and incidence—are fundamental for understanding disease dynamics within a population. These measures enable public health officials, epidemiologists, and researchers to assess the burden of diseases, allocate resources effectively, and design impactful public health policies and interventions.
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
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Transduction01:16

Transduction

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Among the three main modes of HGT—transformation, conjugation, and transduction—transduction is unique in that it is mediated by bacteriophages, or bacterial viruses.Transduction occurs in two ways. Generalized transduction occurs during the lytic cycle of a bacteriophage infection. In this process, bacteriophages infect bacterial cells, replicate within them, and ultimately cause cell lysis, releasing newly assembled virions. Occasionally, random fragments of the bacterial genome...
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相关实验视频

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Application of I TASSER, trRosetta, UCSF Chimera, HADDOCK server, and HEX loria for De Novo and In Silico Design of Proteins
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当一种新出现的疾病成为流行病时

Graham F Medley1, Anna Vassall2

  • 1Department of Global Health and Development, London School of Hygiene and Tropical Medicine, WC1E 7HT London, UK. graham.medley@lshtm.ac.uk.

Science (New York, N.Y.)
|July 15, 2017
PubMed
概括

疫情得到了大量关注和资金,导致成功的根除努力. 然而,地方性疾病给公共卫生带来了更大的负担,

科学领域:

  • 公共卫生
  • 流行病学
  • 传染性疾病

背景情况:

  • 像艾滋病毒 (80年代初) 和埃博拉 (2014) 这样的流行病引发了大量的政府投资,公众关注和迅速行动.
  • 地方性疾病,如艾滋病毒 (2017) 和结核病,往往无法维持类似的关注和资源.
  • 一个显著的悖论存在于当地流行病总体上比流行病更严重的公共卫生负担.

研究的目的:

  • 突出公众和政府关注流行病和流行病之间的差异.
  • 强调流行传染病对公众健康的重大影响.
  • 分析有助于成功管理流行病的因素.

主要方法:

  • 历史流行病反应和当前流行病负担的比较分析.
  • 对某些流行病和特有病的公共卫生投资和媒体关注的审查.
  • 检查传染病对全球健康的长期影响.

主要成果:

  • 流行病在历史上促使采取果断行动,即使没有先进的生物医学干预措施,
  • 地方性疾病尽管累积负担较高,但仍难以保持公众和政治关注度.
  • 艾滋病毒是一个独特的病例,从流行病转变为流行病,而许多长期存在的流行病继续主导传染病领域.

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Vector Competence Analyses on Aedes aegypti Mosquitoes using Zika Virus
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A Mouse Model for the Transition of Streptococcus pneumoniae from Colonizer to Pathogen upon Viral Co-Infection Recapitulates Age-Exacerbated Illness
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结论:

  • 目前对传染病的处理方式不成比例地倾向于流行病的威胁而不是持续存在的流行病负担.
  • 有效的流行病管理策略提供了有价值的教训,以应对持续存在的流行病挑战.
  • 需要重新评估资源分配和公共卫生重点,以充分解决传染病威胁的全部问题.