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Updated: Feb 26, 2026

Spatio-Temporal Manipulation of Small GTPase Activity at Subcellular Level and on Timescale of Seconds in Living Cells
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Published on: March 9, 2012

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通过Rbfox的拼接激活需要通过其氨酸丰富的域进行自我聚合

Yi Ying1, Xiao-Jun Wang2, Celine K Vuong1

  • 1Molecular Biology Interdepartmental Doctoral Program, University of California, Los Angeles, Los Angeles, CA, USA; Molecular Biology Institute, University of California, Los Angeles, Los Angeles, CA, USA.

Cell
|July 15, 2017
PubMed
概括

Rbfox蛋白通过它们的C端域与大型拼接调节器组合 (LASR). 这种高阶组合对于正常的RNA拼接至关重要,与病态蛋白质聚合物不同.

关键词:
结合RNA的蛋白质替代拼接阶段分离转录后基因调节蛋白质聚合物蛋白与蛋白的相互作用

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